Nuclepore Hydrophilic Membrane, 12.0um Pore Size, 25mm Circle, 100/Pk SKU: 10418506

Polycarbonate Track-Etched (PCTE) Membrane Filters - 10418506

The Whatman 10418506 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. From a technical standpoint, verified 12.0 pore distribution across the Hydrophobic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. In turn, from raw polymer through final inspection, the manufacturing process is designed to ensure that every membrane disc meets the performance specifications of its grade designation.

Material Specifications

• Track-etched Polycarbonate membranes feature perfectly cylindrical pores for absolute fractionation.
• Low protein binding and biologically inert surface properties make track-etched Polycarbonate compatible with cell biology and cytology workflows.
• Bulk format reduces per-unit packaging waste and cost, appropriate for routine particulate removal and clarification where aseptic handling is not specified.
• Optically clear construction enables direct on-membrane visualization of captured particles without transfer or additional preparation.
• Offer a smooth, flat glass-like surface specifically designed for microscopy analysis.

Environmental monitoring programs where sample-to-sample comparability determines trend validity benefit directly from the lot-level consistency of these membranes, removing the filter as a variable in your long-term data sets. Specifically, the precisely etched, cylindrical pores of track-etched polycarbonate provide the sharpest size cutoff of any polymeric membrane, giving you near-absolute retention at the rated pore diameter for applications where size-selective capture is critical. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

N/A

Color

translucent

Diameter

25mm

Extractables

very low

Filtration Area

4.91cm²

Flow Rate

30 L (Air)

Grid (Yes/No)

No

Material

Polycarbonate (PC)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

140°C

Membrane Thickness (µm)

6–11um

Pack Count

100

pH Range

2-11

Pore Size (µm)

12

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophobic

• Exosome Isolation - Separates extracellular vesicles from larger cell debris using defined pore sizes, preventing contamination in RNA analysis.
• Legionella Recovery - Captures bacteria from hot water samples on a flat plane for direct fluorescent antibody staining and microscope counting.
• Chemotaxis Migration - Acts as a precise barrier in Boyden chambers to measure cell migration towards chemoattractants without passive diffusion.
• Erythrocyte Deformability - Mimics capillary dimensions to test red blood cell flexibility and rheology in clinical hemorheology research.
• Asbestos Analysis - Provides a smooth, flat surface for collecting airborne fibers, allowing for direct counting via phase-contrast light microscopy.
• Parasite Detection - Concentrates blood samples to detect microfilariae on a transparent surface, simplifying identification without staining.