MCE Circle ME Range (ME 25), Plain, 0.45um Pore Size, 25mm, 100pk SKU: 10401606

Mixed Cellulose Ester (MCE) Membrane Filters - 10401606

The Whatman 10401606 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. Quality-controlled manufacturing ensures the filtration medium delivers the retention efficiency and throughput that demanding laboratory protocols require. Accordingly, lot-level verification of pore size, flow rate, and physical dimensions ensures that membrane performance remains predictable when scaling from method development to routine analysis.

Material Specifications

• Low tare weight and complete solubility in organic solvents make MCE the standard membrane for gravimetric particulate analysis where method specifications demand minimal blank correction.
• Economical bulk packaging supports laboratories with high consumable throughput where individual sterile wrapping is unnecessary.
• Mixed Cellulose Ester membranes combine cellulose acetate and cellulose nitrate polymers to deliver a smoother, more flexible membrane surface than pure cellulose nitrate.
• Known for excellent wetting properties and high flow rates in aqueous filtration.
• Hydrophilic by nature, the MCE membrane structure supports high non-specific adsorption for effective organism capture.

Microbial enumeration methods require complete retention at the rated pore size and a surface that supports colony growth without inhibition, and the membrane specifications above confirm both requirements for your culture-based workflows. The uniform surface structure of mixed cellulose ester membranes provides the optically flat background that your microscopy and particulate analysis methods require for accurate visualization and particle counting. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35.0psi

Color

white

Diameter

25mm

Extractables

low

Filtration Area

4.91cm²

Flow Rate

60ml (Water)

Grid (Yes/No)

No

Material

Mixed Cellulose Esters (MCE)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

130°C

Membrane Thickness (µm)

135um

Pack Count

100

pH Range

4-8

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.
• Chemotaxis Assays - Acts as a barrier in Boyden chambers, allowing cells to migrate through defined pores towards a chemoattractant source.
• Aerosol Analysis - Dissolves completely in acid digestion, allowing for the total chemical analysis of captured airborne metal particulates.
• Yeast & Mold Monitoring - Optimized for the recovery of larger fungal organisms in beverage testing, providing a clear background for ID.
• Microscopy mounting - Can be made transparent with immersion oil, allowing for direct light microscopy of retained particles on the surface.
• Aqueous Filtration - Biologically inert composition provides high flow rates and consistent reliability for routine laboratory fluid processing.