RC Membrane (RC58), 0.2um Pore Size, 50mm Circle (100 pcs) SKU: 10410314

Regenerated Cellulose (RC) Membrane Filters - 10410314

The Whatman 10410314 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Developed with critical workflows in mind, reproducible separation characteristics define the membrane structure, protecting downstream instruments and preserving sample integrity throughout the filtration process. Precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Non-sterile configuration is suited for analytical sample preparation, mobile phase filtration, and other workflows where pre-sterilization is not required.
• Regenerated Cellulose offers excellent chemical resistance to both aqueous and organic solvents.
• Minimal extractable levels make Regenerated Cellulose a reliable choice for analytical applications where background interference must be minimized.
• Mechanically stable and hydrophilic, often used for HPLC mobile phase degassing.
• A premium choice for broad chemical compatibility without requiring pre-wetting.

When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. With this in mind, regenerated cellulose offers the lowest non-specific protein binding of any cellulose-based membrane, ensuring that your biological filtrates retain analyte concentrations close to the original sample without significant adsorptive loss. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40-65psi

Color

white

Diameter

50mm

Extractables

very low

Filtration Area

19.63cm²

Flow Rate

40ml (Water)

Grid (Yes/No)

No

Material

Regenerated Cellulose (RC)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

180°C

Membrane Thickness (µm)

160um

Pack Count

100

pH Range

3-12

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Tissue Extract Clarification - Handles lipid-rich tissue extracts well, preventing the premature fouling often seen with hydrophobic membrane types.
• Ultraclean Solvent Prep - Filters HPLC mobile phases with high efficiency, ensuring no extractables interfere with sensitive UV detection downstream.
• Microplastic Collection - Filters water samples to capture microplastic fibers, providing a smooth background for microscopic categorization.
• Dialysis Membrane Sheet - Used in custom dialyzers to facilitate buffer exchange and desalting of protein solutions via passive diffusion.
• Multiplex Bead Assays - Retains microspheres in flow-through assays while allowing the sample matrix to wash away without trapping the beads.
• Particle Sizing - Used in automated particle counters to provide a clean, non-shedding background for accurate contaminant sizing data.