Pall
Supor 450 Membrane Disc Filters, 0.45um - 142mm, No Tab, 25/Pk SKU: 66553

Supor (PES) Membrane Filters - 66553

Precision-manufactured Hydrophilic membrane with a verified 0.45 pore structure delivers consistent retention performance across demanding laboratory filtration workflows. Complementing this, uniform pore size distribution across the membrane surface ensures consistent particle retention from center to edge, supporting reproducible analytical and preparative results. Ultimately, consistent surface properties across the full membrane area support uniform particle capture and reliable results in gravimetric, microscopic, and culture-based analytical workflows.

Material Specifications

• Rigorous quality controls validate retention performance at rated pore sizes, positioning Supor as a primary membrane choice for critical filtration in biopharmaceutical production.
• Packaged without sterilization for applications where downstream sterility is achieved by other means or is not a process requirement.
• Broad chemical compatibility across pH 1–14 enables Supor membranes to process acidic, neutral, and alkaline solutions without membrane degradation.
• Ultra-low protein binding preserves the biological activity of growth factors, cytokines, and other sensitive proteins during membrane passage.
• Asymmetric pore architecture concentrates the retentive skin at the upstream surface while maintaining an open substructure for sustained throughput under vacuum or pressure.

Environmental monitoring programs where sample-to-sample comparability determines trend validity benefit directly from the lot-level consistency of these membranes, removing the filter as a variable in your long-term data sets. Complete specification documentation for this device supports the traceability requirements of your quality system, providing the recorded evidence of consumable performance that auditors and method reviewers expect to see. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Color

White

Diameter

142mm

Extractables

< 2% (Passes USP Class VI)

Filtration Area

158.37cm²

Flow Rate

65 mL/min/cm²

Grid (Yes/No)

No

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

130 – 160µm

Pack Count

25

pH Range

1-14

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Support Material

N/A

Wettability

Hydrophilic

• High-Speed Vac Filtration - Accelerates the processing of liters of media in vacuum cups, significantly reducing hood time for lab staff.
• Exosome Purification - Clarifies cell supernatants prior to exosome isolation, removing cellular debris without trapping the nanovesicles.
• Bioprocess Clarification - Supor disc membranes remove fine particulates from cell culture harvests, protecting downstream purification steps.
• Diagnostic Kit Reagents - Clarifies high-value diagnostic buffers in manufacturing, ensuring lot-to-lot consistency and particle-free reagents.
• Gene Therapy Buffers - Filters large volumes of viral vector buffers with low protein binding, preserving the viral titer effectively.
• Buffer Filtration - Provides fast flow rates and low protein binding, ideal for the rapid processing of laboratory buffers and solutions.