Supor 450Membrane Disc Filters, 0.45um - 142mm, Tabbed, 25/Pk SKU: 60177

Supor (PES) Membrane Filters - 60177

Engineered for high retention efficiency and superior chemical stability, the Pall 60177 achieves reliable separation results across a broad range of analytical and preparative applications. Optimized for laboratory use, high flow rate performance reduces processing time in vacuum filtration setups, making Supor the preferred membrane for laboratories filtering multiple liters per session. Ultimately, precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Maximum operating temperature of 55°C accommodates warm sample filtration and elevated-temperature processes that exceed the limits of standard devices.
• Ultra-low protein binding preserves the biological activity of growth factors, cytokines, and other sensitive proteins during membrane passage.
• Asymmetric pore architecture concentrates the retentive skin at the upstream surface while maintaining an open substructure for sustained throughput under vacuum or pressure.
• Rigorous quality controls validate retention performance at rated pore sizes, positioning Supor as a primary membrane choice for critical filtration in biopharmaceutical production.
• Consistent lot-to-lot performance supports standardized filtration protocols, reducing the revalidation burden when transitioning between production lots.

Reproducible particle counting starts with a membrane surface that captures particles uniformly. The pore consistency documented above ensures your counts reflect the sample, not filter variation. Addressing this directly, low extractable levels from the filter medium protect the analytical cleanliness of your filtrate, reducing the background interference that complicates trace-level analyses and forces unnecessary repeat measurements. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Color

White

Diameter

142mm

Extractables

< 2% (Passes USP Class VI)

Filtration Area

158.37cm²

Flow Rate

65 mL/min/cm²

Grid (Yes/No)

No

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

130 – 160µm

Pack Count

25

pH Range

1-14

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Support Material

N/A

Wettability

Hydrophilic

• Gene Therapy Buffers - Filters large volumes of viral vector buffers with low protein binding, preserving the viral titer effectively.
• High-Speed Vac Filtration - Accelerates the processing of liters of media in vacuum cups, significantly reducing hood time for lab staff.
• Stem Cell Media Prep - Filters viscous, growth-factor-rich media without clogging, preserving the critical nutrients needed for cell health.
• Bioprocess Clarification - Supor disc membranes remove fine particulates from cell culture harvests, protecting downstream purification steps.
• Exosome Purification - Clarifies cell supernatants prior to exosome isolation, removing cellular debris without trapping the nanovesicles.
• Automated Media Fill - Integrated into automated media dispensing systems, providing reliable flow rates that prevent machine timeouts.