GLA-5000 PVC Membrane Disc Filters - 5um, 37mm, 100/Pk SKU: 66469

Nylon Membrane Filters - 66469

Engineered for high retention efficiency and superior chemical stability, the Pall 66469 achieves reliable separation results across a broad range of analytical and preparative applications. Manufactured to exacting specifications, precision membrane geometry balances retention sharpness with sustainable flow rates, minimizing the pressure buildup that leads to premature filter replacement. Lot-level verification of pore size, flow rate, and physical dimensions ensures that membrane performance remains predictable when scaling from method development to routine analysis.

Material Specifications

• Alkaline-resistant and compatible with a broad range of aqueous buffers used in pharmaceutical and biotechnology laboratories.
• Flexible and durable, eliminating the need for wetting agents that could contaminate samples.
• High mechanical strength allows Nylon membranes to withstand elevated differential pressures without structural deformation.
• Naturally hydrophilic and constructed with high tensile strength, Nylon provides reliable performance without pre-wetting in aqueous applications.
• Ideal for filtering aqueous biological solutions and mobile phases.

When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. Specifically, natural wettability lets you begin filtration immediately upon sample contact, eliminating the bubble formation and flow interruption that hydrophobic membranes introduce without pre-treatment. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1psi

Color

White

Diameter

37mm

Extractables

< 0.5% (Low Ash)

Filtration Area

10.75cm²

Flow Rate

14 LPM (Air)

Grid (Yes/No)

No

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

52°C

Membrane Thickness (µm)

135 – 165µm

Pack Count

25

pH Range

3-14

Pore Size (µm)

5

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Support Material

N/A

Wettability

Hydrophobic

• Radiolabeled Assays - Retains radiolabeled DNA/RNA fragments efficiently, ensuring accurate quantification in molecular biology experiments.
• Solid Phase Extraction - Acts as a frit or barrier in custom extraction columns, retaining sorbent beds while allowing solvent to pass through.
• Gene Mapping Support - Provides a stable, charge-modified surface for DNA immobilization, facilitating precise gene mapping and analysis steps.
• Southern Blot Transfer - Binds nucleic acids strongly during capillary transfer, providing a durable matrix for repeated hybridization cycles.
• Alkaline Filtration - Withstands high-pH solutions during industrial fluid processing, offering durability where other polymers might degrade.
• Solvent Mobilization - Clarifies organic mobile phases in glass vacuum holders, preventing particulate damage to sensitive HPLC pump seals.