RC Membrane (RC55), 0.45um Pore Size, 25mm Circle (100 pcs) SKU: 10410206

Regenerated Cellulose (RC) Membrane Filters - 10410206

The Whatman 10410206 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. Designed for laboratory performance, reproducible separation characteristics define the membrane structure, protecting downstream instruments and preserving sample integrity throughout the filtration process. Consistent surface properties across the full membrane area support uniform particle capture and reliable results in gravimetric, microscopic, and culture-based analytical workflows.

Material Specifications

• Minimal extractable levels make Regenerated Cellulose a reliable choice for analytical applications where background interference must be minimized.
• Packaged without sterilization for applications where downstream sterility is achieved by other means or is not a process requirement.
• A premium choice for broad chemical compatibility without requiring pre-wetting.
• Resistant to a wide range of organic solvents including alcohols, ethers, and hydrocarbons that degrade cellulose-based alternatives.
• Mechanically stable and hydrophilic, often used for HPLC mobile phase degassing.

When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. To address this, low binding combined with high flow rate makes RC particularly effective when you need to filter dilute biological samples where both recovery and throughput matter to your results. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

50-80psi

Color

white

Diameter

25mm

Extractables

very low

Filtration Area

4.91cm²

Flow Rate

11ml (Water)

Grid (Yes/No)

No

Material

Regenerated Cellulose (RC)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

180°C

Membrane Thickness (µm)

160um

Pack Count

100

pH Range

3-12

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Refractive Index Prep - Ensures absolute optical clarity in filtrates, which is critical for accurate measurements in refractive index detectors.
• Organic Solvent Cleaning - Compatible with DMSO and other harsh organics, making it perfect for combinational chemistry sample clarification.
• Tissue Extract Clarification - Handles lipid-rich tissue extracts well, preventing the premature fouling often seen with hydrophobic membrane types.
• Multiplex Bead Assays - Retains microspheres in flow-through assays while allowing the sample matrix to wash away without trapping the beads.
• Microplastic Collection - Filters water samples to capture microplastic fibers, providing a smooth background for microscopic categorization.
• Particle Sizing - Used in automated particle counters to provide a clean, non-shedding background for accurate contaminant sizing data.