MCE Membrane Filter, 0.45um, 25mm, Nonsterile, 200 Pk SKU: SF14621

Mixed Cellulose Ester (MCE) Membrane Filters - SF14621

The Tisch SF14621 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. Verified 0.45 pore distribution across the hydrophilic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. Precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Hydrophilic by nature, the MCE membrane structure supports high non-specific adsorption for effective organism capture.
• The biologically inert blend of cellulose acetate and cellulose nitrate provides a membrane surface optimized for organism capture and colony enumeration in microbiological assays.
• Mixed Cellulose Ester membranes combine cellulose acetate and cellulose nitrate polymers to deliver a smoother, more flexible membrane surface than pure cellulose nitrate.
• Low tare weight and complete solubility in organic solvents make MCE the standard membrane for gravimetric particulate analysis where method specifications demand minimal blank correction.
• Built-in hydrophilic character allows direct processing of buffers, culture media, and aqueous reagents without membrane conditioning steps.

Microbial enumeration methods require complete retention at rated pore size and a growth-supporting surface. The membrane specifications above confirm both requirements for your culture-based workflows. For this application, naturally hydrophilic MCE wets immediately on contact with aqueous samples, eliminating pre-conditioning and letting you begin filtration as soon as the membrane is seated. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

≥21.8 psi (water, 25°C)

Burst Pressure (psi)

87psi.

Color

White

Diameter

25mm

Extractables

Moderate

Filtration Area

4.91cm²

Flow Rate

≥20 mL/min/cm²

Grid (Yes/No)

No

Incompatibility

Bases, organic solvents

Material

Mixed Cellulose Ester (MCE)

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-120um

Pack Count

200

pH Range

2-10pH

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclave, EtO, Gamma Irradiation

Support Material

PET

Weight

0.07

Wettability

Hydrophilic

• Yeast & Mold Monitoring - Optimized for the recovery of larger fungal organisms in beverage testing, providing a clear background for ID.
• Microscopy mounting - Can be made transparent with immersion oil, allowing for direct light microscopy of retained particles on the surface.
• Gravimetric Analysis - Maintains structural integrity during filtration and drying, providing precise weight measurements of retained particulates.
• Aqueous Filtration - Biologically inert composition provides high flow rates and consistent reliability for routine laboratory fluid processing.
• Black Grid Analysis - Black membrane variants enhance contrast for light-colored colonies, reducing eye strain during manual plate counting.
• Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.